Journal article
Longitudinal trajectory of bacterial vaginosis during pregnancy
American journal of obstetrics and gynecology, v 199(4), pp 431.e1-431.e5
2008
PMID: 18928996
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
This study was undertaken to characterize the course of bacterial vaginosis in pregnancy and to discern the bacterial morphotypes responsible for infection.
Vaginal secretions were obtained in each trimester of pregnancy and were evaluated for bacterial vaginosis by Gram stain, categorized as normal or any of the following:
Lactobacillus deficient,
Gardnerella,
Bacteroides, or
Mobiluncus positive and by Nugent score. Results were evaluated for trends of bacterial vaginosis and Gram stain over pregnancy.
One hundred forty-eight women were evaluated. Seventy-one women (48%) were bacterial vaginosis negative in all trimesters, compared with 14 (9.4%) who were positive throughout pregnancy. Among the 14 women who remained bacterial vaginosis positive, Gram stain findings were
Gardnerella+
Bacteroides+
Lactobacillus, with approximately 50% harboring
Mobiluncus. Few women become bacterial vaginosis positive as pregnancy progressed (6.1%). With each increasing week of pregnancy, the risk of becoming bacterial vaginosis positive decreased (0.93: 0.91-0.95;
P < .001).
In this population, the majority of pregnant women trend toward bacterial vaginosis negative status. Few women are bacterial vaginosis positive across their pregnancy.
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Details
- Title
- Longitudinal trajectory of bacterial vaginosis during pregnancy
- Creators
- Thaddeus P. Waters - MetroHealthJeff M. Denney - Department of Obstetrics and Gynecology, Drexel University College of Medicine, Philadelphia, PALeny Mathew - Drexel UniversityRobert L. Goldenberg - Drexel UniversityJennifer F. Culhane - Drexel University
- Publication Details
- American journal of obstetrics and gynecology, v 199(4), pp 431.e1-431.e5
- Publisher
- Mosby, Inc
- Resource Type
- Journal article
- Language
- English
- Web of Science ID
- WOS:000260045700041
- Scopus ID
- 2-s2.0-52949129163
- Other Identifier
- 991019339576804721
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InCites Highlights
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Obstetrics & Gynecology