Journal article
MIDLINE CEREBRAL MALFORMATIONS AND SCHIZOPHRENIA
The journal of neuropsychiatry and clinical neurosciences, v 5(3), pp 287-293
01 Jun 1993
PMID: 8369638
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
To investigate a possible association of midline cerebral malformations with psychotic disorders, MRI and CT scans were blindly evaluated for 52 patients with schizophrenia, 9 with schizoaffective disease, and 79 consecutive nonpsychotic control subjects. Midline abnormalities were present in 10 of 61 patients (16.4%) versus 4 of 79 control subjects (5.1%; P < 0.05, chi-square). Of 52 schizophrenic patients, 8 had abnormalities of the septum pellucidum (SP): 5 had cavum vergae (CaV), 2 had cavum septum pellucidum (CaSP), and 1 had agenesis of the corpus callosum and SP. Of 9 schizoaffective patients, 2 had SP abnormalities: 1 CaV and 1 CaSP. Abnormalities of the SP, especially CaV, were significantly more frequent in women than in men (P < 0.02, chi-square).
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Details
- Title
- MIDLINE CEREBRAL MALFORMATIONS AND SCHIZOPHRENIA
- Creators
- T F Scott - Drexel UniversityTRP PriceM S GeorgeJ BrillmanW Rothfus
- Publication Details
- The journal of neuropsychiatry and clinical neurosciences, v 5(3), pp 287-293
- Publisher
- AMER PSYCHIATRIC ASSOCIATION
- Number of pages
- 7
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Neurology
- Web of Science ID
- WOS:A1993LU32500007
- Scopus ID
- 2-s2.0-0027265485
- Other Identifier
- 991019183963704721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Clinical Neurology
- Neurosciences
- Psychiatry