Journal article
Magnetic nanoparticle-based approaches to locally target therapy and enhance tissue regeneration in vivo
Nanomedicine (London, England), v 7(9), pp 1425-1442
Sep 2012
PMID: 22994959
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Magnetic-based systems utilizing superparamagnetic nanoparticles and a magnetic field gradient to exert a force on these particles have been used in a wide range of biomedical applications. This review is focused on drug targeting applications that require penetration of a cellular barrier as well as strategies to improve the efficacy of targeting in these biomedical applications. Another focus of this review is regenerative applications utilizing tissue engineered scaffolds prepared with the aid of magnetic particles, the use of remote actuation for release of bioactive molecules and magneto–mechanical cell stimulation, cell seeding and cell patterning.
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Details
- Title
- Magnetic nanoparticle-based approaches to locally target therapy and enhance tissue regeneration in vivo
- Creators
- Richard Sensenig - Department of Surgery, Drexel University College of Medicine, PA 19102, USAYulia Sapir - Avram & Stella Goldstein-Goren Department of Biotechnology Engineering, Ben-Gurion University of the Negev, Beer-Sheva 84105, IsraelCristin MacDonald - School of Biomedical Engineering, Drexel University, PA 19104, USASmadar Cohen - Avram & Stella Goldstein-Goren Department of Biotechnology Engineering, Ben-Gurion University of the Negev, Beer-Sheva 84105, IsraelBoris Polyak - Department of Surgery, Drexel University College of Medicine, PA 19102, USA
- Publication Details
- Nanomedicine (London, England), v 7(9), pp 1425-1442
- Grant note
- R01 HL107771 || HL / National Heart, Lung, and Blood Institute : NHLBI
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Surgery
- Web of Science ID
- WOS:000309032100021
- Scopus ID
- 2-s2.0-84866640090
- Other Identifier
- 991014877928704721
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- Collaboration types
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Biotechnology & Applied Microbiology
- Nanoscience & Nanotechnology