Journal article
Magnetoelastic vibrational biomaterials for real-time monitoring and modulation of the host response
Journal of materials science. Materials in medicine, v 24(4), pp 1093-1104
01 Apr 2013
PMID: 23354739
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Magnetoelastic (ME) biomaterials are ferromagnetic materials that physically deform when exposed to a magnetic field. This work describes the real-time control and monitoring capabilities of ME biomaterials in wound healing. Studies were conducted to demonstrate the capacity of the materials to monitor changes in protein adsorption and matrix stiffness. In vitro experiments demonstrated that ME biomaterials can monitor cell adhesion and growth in real-time, and a long-term in vivo study demonstrated their ability to monitor the host response (wound healing) to an implant and control local cell density and collagen matrix production at the soft tissue-implant interface. This approach represents a potentially self-aware and post-deployment activated biomaterial coating as a means to monitor an implant surface and provide an adjuvant therapy for implant fibrosis.
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Details
- Title
- Magnetoelastic vibrational biomaterials for real-time monitoring and modulation of the host response
- Creators
- E. Vlaisavljevich - Michigan Technological UniversityH. R. Holmes - Michigan Technological UniversityE. L. Tan - Michigan Technological UniversityZ. Qian - Michigan Technological UniversityS. Trierweiler - Michigan Technological UniversityK. G. Ong - Michigan Technological UniversityR. M. Rajachar - Michigan Technological UniversityKevin Li-Teck Ong - School of Biomedical Engineering, Science, and Health Systems (1997-)
- Publication Details
- Journal of materials science. Materials in medicine, v 24(4), pp 1093-1104
- Publisher
- Springer Nature
- Number of pages
- 12
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- School of Biomedical Engineering, Science, and Health Systems
- Web of Science ID
- WOS:000318509100023
- Scopus ID
- 2-s2.0-84876294721
- Other Identifier
- 991019170853004721
UN Sustainable Development Goals (SDGs)
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InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Engineering, Biomedical
- Materials Science, Biomaterials