Journal article
Malignant hyperthermia susceptibility in X-linked muscle dystrophies
Pediatric neurology, v 2(6), pp 356-358
1986
PMID: 3508709
Abstract
To evaluate malignant hyperthermia (MH) susceptibility in X-linked muscular dystrophies, halothane and caffeine contracture tests were performed on muscle fiber bundles from five patients with Duchenne muscular dystrophy (DMD) and two patients with Becker muscular dystrophy (BMD). Two DMD patients and one BMD patient had positive contracture tests. Since a positive contracture test is currently the best indicator of anesthetic susceptibility in the MH population, and episodes of MH in dystrophic patients have been reported, patients with DMD and BMD may be at risk for developing similar anesthetic complications. Awareness of this potential anesthetic risk is of importance because orthopedic interventions are increasingly more common in these patients.
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Details
- Title
- Malignant hyperthermia susceptibility in X-linked muscle dystrophies
- Creators
- Terry D. Heiman-Patterson - Hahnemann University HospitalHoward M. Natter - Hahnemann University HospitalHenry R. Rosenberg - Hahnemann University HospitalJeffrey E. Fletcher - Hahnemann University HospitalAlbert J. Tahmoush - Hahnemann University Hospital
- Publication Details
- Pediatric neurology, v 2(6), pp 356-358
- Publisher
- Elsevier
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Neurology
- Scopus ID
- 2-s2.0-0022897114
- Other Identifier
- 991019173692604721