Journal article
Mammary fat necrosis following radiotherapy in the conservative management of localized breast cancer: Does it matter?
Radiotherapy and oncology, v 97(1), pp 92-94
01 Oct 2010
PMID: 20227125
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Purpose: Fat necrosis is a well-described and relatively common complication arising from post-lumpectomy irradiation of the breast, most commonly breast brachytherapy. We wish to assess the clinical significance of fat necrosis resulting from post-lumpectomy breast irradiation.
Methods: We reviewed the literature to determine the overall incidence and significance of fat necrosis to determine whether or not fat necrosis poses a significant clinical problem.
Results: Fat necrosis occurs in up to one-quarter of patients following post-lumpectomy breast irradiation. Only rarely is invasive intervention required however, it does significantly degrade the quality of all modalities of breast imaging.
Conclusions: Fat necrosis is a common complication of radiotherapy which rarely requires therapeutic intervention. However, post-therapeutic clinical imaging such as mammography, ultrasound and magnetic resonance imaging are affected which may result in additional diagnostic procedures up to and including biopsy. (C) 2010 Elsevier Ireland Ltd. All rights reserved. Radiotherapy and Oncology 97 (2010) 92-94
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Details
- Title
- Mammary fat necrosis following radiotherapy in the conservative management of localized breast cancer: Does it matter?
- Creators
- Mark Trombetta - Allegheny General HospitalVladimir Valakh - Allegheny General HospitalThomas B. Julian - Allegheny General HospitalE. Day Werts - Allegheny General HospitalDavid Parda - Allegheny General Hospital
- Publication Details
- Radiotherapy and oncology, v 97(1), pp 92-94
- Publisher
- Elsevier
- Number of pages
- 3
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Radiation Oncology (and Nuclear Medicine)
- Web of Science ID
- WOS:000283685400017
- Scopus ID
- 2-s2.0-77957879240
- Other Identifier
- 991019169909504721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Oncology
- Radiology, Nuclear Medicine & Medical Imaging