Journal article
Management Strategies during a VA ECMO Run in a Neonate with E. Coli Septic Shock Masquerading as Hypoxic Ischemic Encephalopathy
The Journal of extra-corporeal technology, v 51(2), pp 88-93
Jun 2019
PMID: 31239582
Abstract
Advances in neonatal care for hypoxic respiratory failure, with high-frequency ventilation and inhaled nitric oxide, have led to a decreased need for extracorporeal membrane oxygenation (ECMO). However, neonates resistant to such therapies are more complex and at higher risk of mortality. One such population includes those with hypoxic ischemic encephalopathy (HIE) undergoing controlled hypothermia (CH). We present a challenging case of a full-term neonate with inotrope-resistant
septic shock, profound coagulopathy, hypoxic respiratory failure, and HIE requiring CH and venoarterial (VA) ECMO. We illustrate that family-centered decision-making, ECMO, primary team, and subspecialist support is critical to success. In addition, we share the strategic medical interventions concomitantly used with VA ECMO to aid in the survival of this high-risk infant such as continuous veno-venous hemofiltration with AN69 membrane for cytokine and fluid removal, prostaglandin use to relieve right ventricular strain in malignant pulmonary hypertension, and cautious use of bronchoscopy to assist in lung recruitment.
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Details
- Title
- Management Strategies during a VA ECMO Run in a Neonate with E. Coli Septic Shock Masquerading as Hypoxic Ischemic Encephalopathy
- Creators
- Vilmaris Quinones Cardona - Division of Neonatology, Department of Pediatrics, St. Christopher's Hospital for Children/Drexel University College of Medicine, Philadelphia, PennsylvaniaOgechukwu Menkiti - Division of Neonatology, Department of Pediatrics, St. Christopher's Hospital for Children/Drexel University College of Medicine, Philadelphia, Pennsylvania
- Publication Details
- The Journal of extra-corporeal technology, v 51(2), pp 88-93
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Pediatrics
- Scopus ID
- 2-s2.0-85068834459
- Other Identifier
- 991019173988104721