Journal article
Management of dyslipidaemia in patients with comorbidities-facing the challenge: type 1 diabetes mellitus
European heart journal. Cardiovascular pharmacotherapy, v 11(4), pp 380-386
01 Jul 2025
PMID: 40396997
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Type 1 diabetes is associated with excess cardiovascular risk. In contrast to type 2 diabetes, however, age at the onset of type 1 diabetes and sex are major predictors of cardiovascular risk, while the role of low-density lipoprotein cholesterol (LDL-C) and lipid-lowering therapy is less clear. Since most data on the effects of lipid-lowering treatments are obtained from randomized clinical trials that included very predominantly patients with type 2 diabetes, it is almost impossible to specifically discern endpoints in type 1 diabetes. Inversely, most data specific for type 1 diabetes are obtained from real world findings. Consequently, the evidence on efficacy and safety of lipid-lowering therapies available from randomized clinical trials arises very predominantly from type 2 diabetes. Thus, this specific review summarizes the evidence of lipid-lowering drug classes in reducing cardiovascular risk in patients with type 1 diabetes.
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Details
- Title
- Management of dyslipidaemia in patients with comorbidities-facing the challenge: type 1 diabetes mellitus
- Creators
- Susanne Kaser - Innsbruck Medical UniversityDobromir Dobrev - Baylor College of MedicineBianca Rocca - Department of Medicine, LUM University, 70010 Casamassima (BA), ItalyJuan Carlos Kaski - St George's, University of LondonStefan Agewall - Karolinska InstitutetHeinz Drexel - Vorarlberg Institute for Vascular Investigation and Treatment
- Publication Details
- European heart journal. Cardiovascular pharmacotherapy, v 11(4), pp 380-386
- Publisher
- Oxford University Press
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- College of Medicine
- Web of Science ID
- WOS:001491845900001
- Scopus ID
- 2-s2.0-105010588302
- Other Identifier
- 991022197301104721
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- Collaboration types
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Cardiac & Cardiovascular Systems
- Pharmacology & Pharmacy