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Management of pouch neoplasia: consensus guidelines from the International Ileal Pouch Consortium
Journal article   Peer reviewed

Management of pouch neoplasia: consensus guidelines from the International Ileal Pouch Consortium

Ravi P. Kiran, Gursimran S. Kochhar, Revital Kariv, Douglas K. Rex, Akira Sugita, David T. Rubin, Udayakumar Navaneethan, Tracy L. Hull, Huaibin Mabel Ko, Xiuli Liu, …
The lancet. Gastroenterology & hepatology, v 7(9), pp 871-893
01 Sep 2022
PMID: 35798022
url
https://pure.amsterdamumc.nl/en/publications/aac1909f-745c-4da8-a572-b33fb9c95184View
Open

Abstract

Gastroenterology & Hepatology Life Sciences & Biomedicine Science & Technology
Surveillance pouchoscopy is recommended for patients with restorative proctocolectomy with ileal pouch-anal anastomosis in ulcerative colitis or familial adenomatous polyposis, with the surveillance interval depending on the risk of neoplasia. Neoplasia in patients with ileal pouches mainly have a glandular source and less often are of squamous cell origin. Various grades of neoplasia can occur in the prepouch ileum, pouch body, rectal cuff, anal transition zone, anus, or perianal skin. The main treatment modalities are endoscopic polypectomy, endoscopic ablation, endoscopic mucosal resection, endoscopic submucosal dissection, surgical local excision, surgical circumferential resection and re-anastomosis, and pouch excision. The choice of the treatment modality is determined by the grade, location, size, and features of neoplastic lesions, along with patients' risk of neoplasia and comorbidities, and local endoscopic and surgical expertise.

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Collaboration types
Domestic collaboration
International collaboration
Web of Science research areas
Gastroenterology & Hepatology
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