Journal article
Mass action kinetics of virus-cell aggregation and fusion
Biophysical journal, v 54(3), pp 449-462
01 Sep 1988
PMID: 3207833
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Abstract
A simple approximate solution for the mass action kinetics of small particles (viruses or vesicles) binding to large particles (cells) and their subsequent fusion has been derived. The solution is evaluated in terms of the measurable fluorescence changes expected when the virus or vesicles are labeled with fluorescent probes, which are diluted into the cellular membrane by fusion. Comparison with numerical integrations shows that the approximate solution is extremely accurate. Analytic simplifications for a variety of special cases of this general problem are also shown.
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Details
- Title
- Mass action kinetics of virus-cell aggregation and fusion
- Creators
- J Bentz - University of California, San FranciscoS Nir - University of California, San FranciscoD G Covell - University of California, San Francisco
- Publication Details
- Biophysical journal, v 54(3), pp 449-462
- Publisher
- Elsevier
- Grant note
- GM-31506 / NIGMS NIH HHS
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Biology
- Web of Science ID
- WOS:A1988P969000009
- Scopus ID
- 2-s2.0-0023707810
- Other Identifier
- 991021463457104721
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- Collaboration types
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Biophysics