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Journal article
Maternal Exposure to Occupational Asthmagens During Pregnancy and Autism Spectrum Disorder in the Study to Explore Early Development
Journal of autism and developmental disorders, v 46(11), pp 3458-3468
01 Nov 2016
PMID: 27511194
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Maternal immune activity has been linked to children with autism spectrum disorder (ASD). We examined maternal occupational exposure to asthma-causing agents during pregnancy in relation to ASD risk. Our sample included 463 ASD cases and 710 general population controls from the Study to Explore Early Development whose mothers reported at least one job during pregnancy. Asthmagen exposure was estimated from a published job-exposure matrix. The adjusted odds ratio for ASD comparing asthmagen-exposed to unexposed was 1.39 (95 % CI 0.96-2.02). Maternal workplace asthmagen exposure was not associated with ASD risk in this study, but this result does not exclude some involvement of maternal exposure to asthma-causing agents in ASD.
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Details
- Title
- Maternal Exposure to Occupational Asthmagens During Pregnancy and Autism Spectrum Disorder in the Study to Explore Early Development
- Creators
- Alison B. Singer - BloombergGayle C. Windham - California Department of Public HealthLisa A. Croen - Kaiser PermanenteJulie L. Daniels - University of North Carolina at Chapel HillBrian K. Lee - Drexel UniversityYinge Qian - Kaiser PermanenteDiana E. Schendel - Aarhus UniversityM. Daniele Fallin - BloombergIgor Burstyn - Drexel University
- Publication Details
- Journal of autism and developmental disorders, v 46(11), pp 3458-3468
- Publisher
- Springer Nature
- Number of pages
- 11
- Grant note
- U01DD001205 / National Center on Birth Defects and Developmental Disabilities; United States Department of Health & Human Services; Centers for Disease Control & Prevention - USA T32ES007018 / NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Environmental Health Sciences (NIEHS) U10DD000184 / CENTERS FOR DISEASE CONTROL AND PREVENTION; United States Department of Health & Human Services; Centers for Disease Control & Prevention - USA T32ES007018 / NIEHS; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Environmental Health Sciences (NIEHS) R155-2014-1724 / Lundbeck Foundation; Lundbeckfonden U10DD000180; U10DD000181; U10DD000182; U10DD000183; U10DD000184; U10DD000498 / Centers for Disease Control and Prevention; United States Department of Health & Human Services; Centers for Disease Control & Prevention - USA 8576 / Autism Speaks Dennis Weatherstone Predoctoral Fellowship
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Epidemiology and Biostatistics; A.J. Drexel Autism Institute; Environmental and Occupational Health
- Web of Science ID
- WOS:000386782700007
- Scopus ID
- 2-s2.0-84981287137
- Other Identifier
- 991019168864004721
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- Collaboration types
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Psychology, Developmental