Journal article
Mechanical Properties of Ultrahigh Molecular Weight PHEMA Hydrogels Synthesized Using Initiated Chemical Vapor Deposition
Biomacromolecules, v 11(8), pp 2116-2122
01 Aug 2010
PMID: 20690719
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
In this work, poly(2-hydroxyethyl methacrylate) (PHEMA), a widely used hydrogel, is synthesized using initiated chemical vapor deposition (iCVD), a one-step surface polymerization that does not use any solvents. iCVD synthesis is capable of producing linear stoichiometric polymers that are free from entrained unreacted monomer or solvent and, thus, do not require additional purification steps. The resulting films, therefore, are found to be noncytotoxic and also have low nonspecific protein adsorption. The kinetics of iCVD polymerization are tuned so as to achieve rapid deposition rates (similar to 1.5 mu m/min), which in turn yield ultrahigh molecular weight polymer films that are mechanically robust with good water transport and swellability. The films have an extremely high degree of physical chain entanglement giving rise to high tensile modulus and storage modulus without the need for chemical cross-linking that compromises hydrophilicity.
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Details
- Title
- Mechanical Properties of Ultrahigh Molecular Weight PHEMA Hydrogels Synthesized Using Initiated Chemical Vapor Deposition
- Creators
- Ranjita K. Bose - Drexel UniversityKenneth K. S. Lau - Drexel University
- Publication Details
- Biomacromolecules, v 11(8), pp 2116-2122
- Publisher
- American Chemical Society; Washington, DC
- Number of pages
- 7
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Chemical and Biological Engineering
- Web of Science ID
- WOS:000280583400029
- Scopus ID
- 2-s2.0-77955561950
- Other Identifier
- 991019168599404721
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InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Biochemistry & Molecular Biology
- Chemistry, Organic
- Polymer Science