Journal article
Medial prefrontal brain activity correlates with emerging symptoms of anxiety and depression in late adolescence: A fNIRS study
Developmental psychobiology, v 63(7), pp e22199-n/a
01 Nov 2021
PMID: 34674240
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
The brain undergoes dramatic changes over the course of the adolescent years, and these developmental changes are implicated in the emergence of disorders that involve negative emotionality. Late adolescence might be the window within which brain networks manifest vulnerabilities to depressive and anxiety symptomology; particularly within the prefrontal cortex (PFC), which houses emotional control (dorsolateral) and emotional processing (medial) nodes. Given the comorbidity of depressive and anxious symptomology, it may be that the neural signature is similar for both within the developing PFC. In a sample of 67 adolescents (M = 15.97 years, SD = 1.36), we used functional near-infrared spectroscopy (fNIRS) to examine the neural signature of emergent anxiety and depressive symptoms among younger and older adolescents. We further examined the extent to which neural signatures of anxiety and depressive symptoms within the PFC were similar or different. Findings revealed that self-reported anxiety and depressive symptoms were highly correlated, and that the neural signatures of both within the PFC were similar, corresponding with the medial subregions of the PFC (i.e., those involved in evaluative processing). These findings were evident only in later adolescence, suggesting the possibility of a common vulnerability for anxiety and depressive disorders emerging around this developmental window.
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Details
- Title
- Medial prefrontal brain activity correlates with emerging symptoms of anxiety and depression in late adolescence: A fNIRS study
- Creators
- Mia Papasideris - University of WaterlooHasan Ayaz - Drexel UniversityPeter A. Hall - University of Waterloo
- Publication Details
- Developmental psychobiology, v 63(7), pp e22199-n/a
- Publisher
- Wiley
- Number of pages
- 13
- Grant note
- Social Sciences Research Council of Canada (SSRHC) Natural Sciences and Engineering Research Council of Canada (NSERC)
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- School of Biomedical Engineering, Science, and Health Systems
- Web of Science ID
- WOS:000709481800004
- Scopus ID
- 2-s2.0-85117416864
- Other Identifier
- 991019168676504721
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- Collaboration types
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Developmental Biology
- Psychology