Journal article
Medial prefrontal cortex hyperactivation during social exclusion in borderline personality disorder
Psychiatry research. Neuroimaging, v 181(3), pp 233-236
2010
PMID: 20153143
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Frontal systems dysfunction and abandonment fears represent central features of borderline personality disorder (BPD). BPD subjects (
n
=
10) and matched non-psychiatric comparison subjects (
n
=
10) completed a social–cognitive task with two confederates instructed to either include or exclude subjects from a circumscribed interaction. Evoked cerebral blood oxygenation in frontal cortex was measured using 16-channel functional near infrared spectroscopy. BPD subjects showed left medial prefrontal cortex hyperactivation during social exclusion suggesting potential dysfunction of frontolimbic circuitry.
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Details
- Title
- Medial prefrontal cortex hyperactivation during social exclusion in borderline personality disorder
- Creators
- Anthony C Ruocco - Department of Psychology, Drexel University, Philadelphia, PA, United StatesJohn D Medaglia - Department of Psychology, Drexel University, Philadelphia, PA, United StatesJennifer R Tinker - Department of Psychology, Drexel University, Philadelphia, PA, United StatesHasan Ayaz - School of Biomedical Engineering, Science & Health Systems, Drexel University, Philadelphia, PA, United StatesEvan M Forman - Department of Psychology, Drexel University, Philadelphia, PA, United StatesCory F Newman - Department of Psychiatry, University of Pennsylvania, Philadelphia, PA, United StatesJ. Michael Williams - Department of Psychology, Drexel University, Philadelphia, PA, United StatesFrank G Hillary - Department of Psychology, The Pennsylvania State University, University Park, PA, United StatesSteven M Platek - School of Biological Sciences, The University of Liverpool, United KingdomBanu Onaral - School of Biomedical Engineering, Science & Health Systems, Drexel University, Philadelphia, PA, United StatesDouglas L Chute - Department of Psychology, Drexel University, Philadelphia, PA, United States
- Publication Details
- Psychiatry research. Neuroimaging, v 181(3), pp 233-236
- Publisher
- Elsevier Ireland Ltd
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Psychological and Brain Sciences (Psychology); Pharmacology and Physiology; School of Biomedical Engineering, Science, and Health Systems; Center for Weight, Eating and Lifestyle Science (WELL) [Historical]
- Web of Science ID
- WOS:000275986200010
- Scopus ID
- 2-s2.0-76749156678
- Other Identifier
- 991014877979404721
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- Collaboration types
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Clinical Neurology
- Neuroimaging
- Psychiatry