Journal article
Metabolomics of bronchopulmonary dysplasia
Clinica chimica acta, v 500, pp 109-114
01 Jan 2020
PMID: 31689411
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
The pathogenesis of Bronchopulmonary dysplasia (BPD) remains poorly understood. It is a multifactorial disease having a genetic-environmental basis. Although attempts have been made to identify a biomarker, none have been validated for clinical use to date. Metabolomics is a promising field of the "omics technologies" that could allow for better understanding of the pathogenesis and underlying mechanisms of BPD as well as facilitate detection of biomarkers. Identification of these biomarkers would improve diagnosis, identify patients in early disease stages and potentially target intervention. This review focuses on the evidence arising from metabolomics and its interaction with microbiomics and pharmacology with respect to pathogenesis and treatment options for this multifactorial complex disease.
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Details
- Title
- Metabolomics of bronchopulmonary dysplasia
- Creators
- Fiammetta Piersigilli - Cliniques Universitaires Saint-LucVineet Bhandari - Drexel University
- Publication Details
- Clinica chimica acta, v 500, pp 109-114
- Publisher
- Elsevier
- Number of pages
- 6
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Pediatrics
- Web of Science ID
- WOS:000509612600016
- Scopus ID
- 2-s2.0-85075354692
- Other Identifier
- 991019167454204721
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- Collaboration types
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Medical Laboratory Technology