Journal article
Metastatic Invasive Ductal Carcinoma Presenting as Unilateral Adrenal Incidentaloma
AACE Endocrinology and Diabetes, v 12(3), pp 169-173
01 Sep 2025
PMID: 41048698
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
The widespread use of cross-sectional imaging has led to increased detection of adrenal incidentalomas (AI), most of which are benign. However, a small fraction of AIs are malignant, with a significantly higher risk in patients with a history of cancer.
Sixty-nine-year-old woman with a remote history of invasive ductal breast carcinoma and thyroid carcinoma in remission presented with chronic abdominal pain. Imaging revealed 2 enlarging, right adrenal nodules with indeterminate features and no uptake on PET-CT. Hormonal tests indicated a nonfunctioning adrenal mass. Due to continued growth, she underwent laparoscopic adrenalectomy. Histopathology revealed metastatic breast carcinoma, and she subsequently initiated systemic chemotherapy.
This case highlights the diagnostic challenges posed by AIs in patients with known cancer and provides valuable insights into the detection and management of adrenal metastases.
Timely surgical intervention allowed for definitive diagnosis and appropriate oncologic management, highlighting the importance of individualized evaluation and multidisciplinary decision-making in cases of AIs.
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Details
- Title
- Metastatic Invasive Ductal Carcinoma Presenting as Unilateral Adrenal Incidentaloma
- Creators
- Ashni Dharia - Allegheny General HospitalKurlya Yan - Allegheny General HospitalSaira Varghese Mammen - Allegheny General HospitalMadeline Myers - Allegheny Health NetworkJanice Ahn - Allegheny General HospitalGayatri Jaiswal - Allegheny General Hospital
- Publication Details
- AACE Endocrinology and Diabetes, v 12(3), pp 169-173
- Publisher
- Elsevier Inc
- Number of pages
- 5
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- General Internal Medicine
- Web of Science ID
- WOS:001585564700011
- Scopus ID
- 2-s2.0-105012210525
- Other Identifier
- 991022138573404721
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- Web of Science research areas
- Endocrinology & Metabolism