Journal article
Methodological Issues in Nutritional Epidemiology Research-Sorting Through the Confusion
Current cardiovascular risk reports, v 12(2)
01 Feb 2018
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Purpose of Review Our purpose was to discuss the methodological limitations of observational nutritional epidemiology research, using observational studies on coffee intake and health as a case example.
Recent Findings A number of recent observational studies on the potential health effects of daily coffee intake have reported protective associations between higher coffee intake and a variety of health outcomes, including death. This is inconsistent with the findings from classic studies showing an increased risk of coronary heart disease events, performed in young adults with a homogeneous education level, and adjusting for tobacco use.
Summary Many nutritional epidemiological studies have important limitations, which limit their validity. These include the use of prevalent user designs, risk of reverse causality, measurement error particularly of the exposure of interest, and residual confounding by socioeconomic status. In this review, we discuss these potential issues and provide constructive recommendations intended to help minimize them.
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Details
- Title
- Methodological Issues in Nutritional Epidemiology Research-Sorting Through the Confusion
- Creators
- Miguel Cainzos-Achirica - Johns Hopkins UniversityUsama Bilal - University of AlcaláKaran Kapoor - Johns Hopkins UniversityRenato Quispe Ayala - Johns Hopkins UniversityJohn W. McEvoy - BloombergManel Pladevall-Vila - RTI Hlth Solut, Pharmacoepidemiol & Risk Management, Barcelona, SpainRoger S. Blumenthal - Johns Hopkins UniversityMichael J. Blaha - Johns Hopkins University
- Publication Details
- Current cardiovascular risk reports, v 12(2)
- Publisher
- Springer Nature
- Number of pages
- 9
- Grant note
- FDA; United States Department of Health & Human Services NIH; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA Siemens; Siemens AG Regeneron Medimmune; AstraZeneca Novartis Akcea Amgen Sanofi AHA; American Heart Association Aetna Foundation
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Urban Health Collaborative
- Web of Science ID
- WOS:000426743700002
- Scopus ID
- 2-s2.0-85041114186
- Other Identifier
- 991019167426104721
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- Collaboration types
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Cardiac & Cardiovascular Systems