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Microbiological and chemical methods in the asymmetric oxidation of sulfides: A comparative study for the preparation of ( S)-vinyl sulfoxides
Journal article   Peer reviewed

Microbiological and chemical methods in the asymmetric oxidation of sulfides: A comparative study for the preparation of ( S)-vinyl sulfoxides

Claude Rossi, Annie Fauve, Michel Madesclaire, Danielle Roche, Franklin A. Davis and R. Thimma Reddy
Tetrahedron: asymmetry, v 3(5), pp 629-636
1992

Abstract

The enantiogenicity of biological and chemical oxidation at the sulfur atom was studied on a series of prochiral vinyl sulfides for the preparation of sulfoxides of ( S)-absolute configuration. Using either fungal cultures, Sharpless-modified reagent or chiral oxaziridine, the enantiomeric excesses varied according to the substrate's steric and/or electronic structure; the three methods were complementary. [Display omitted] [Display omitted] [Display omitted] [Display omitted] [Display omitted]

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Collaboration types
Domestic collaboration
International collaboration
Web of Science research areas
Chemistry, Inorganic & Nuclear
Chemistry, Organic
Chemistry, Physical
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