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Accepted (AM)Open Access (License Unspecified), Open
Journal article
Microcantilevers modified by specific peptide for selective detection of trimethylamine
Biosensors & bioelectronics, v 30(1), pp 140-144
2011
PMID: 22000756
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
We report a biosensor based on a microcantilever that is modified by a specific peptide for highly selective detection of trimethylamine (TMA). The assay is based on binding-induced bending of the peptide functionalized microcantilevers. The sensor is selectively responsive to TMA. The amplitude of microcantilever bending at equilibrium is a function of the concentration of TMA with a dynamic range from 8
ppm to 800
ppm. The detection limit is approximately 8
ppm. There is a good intra-sensor and an acceptable inter-sensor reproducibility as evidenced by the standard deviation of 5% and 15%, respectively.
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Details
- Title
- Microcantilevers modified by specific peptide for selective detection of trimethylamine
- Creators
- Xin Huang - Chinese Academy of Inspection and QuarantineMingfu Li - Chinese Academy of Inspection and QuarantineXiaohe Xu - Drexel UniversityHongjun Chen - Chinese Academy of Inspection and QuarantineHai-Feng Ji - Drexel UniversityShuifang Zhu - Chinese Academy of Inspection and Quarantine
- Publication Details
- Biosensors & bioelectronics, v 30(1), pp 140-144
- Publisher
- Elsevier
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Chemistry
- Web of Science ID
- WOS:000297610200022
- Scopus ID
- 2-s2.0-80755132833
- Other Identifier
- 991019330624104721
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- Collaboration types
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Biophysics
- Biotechnology & Applied Microbiology
- Chemistry, Analytical
- Electrochemistry
- Nanoscience & Nanotechnology