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Microfluidic hydrogels for tissue engineering
Journal article   Peer reviewed

Microfluidic hydrogels for tissue engineering

Guo You Huang, Li Hong Zhou, Qian Cheng Zhang, Yong Mei Chen, Wei Sun, Feng Xu and Tian Jian Lu
Biofabrication, v 3(1), pp 012001-1-13
01 Mar 2011
PMID: 21372342

Abstract

Engineering Engineering, Biomedical Materials Science Materials Science, Biomaterials Science & Technology Technology
With advanced properties similar to the native extracellular matrix, hydrogels have found widespread applications in tissue engineering. Hydrogel-based cellular constructs have been successfully developed to engineer different tissues such as skin, cartilage and bladder. Whilst significant advances have been made, it is still challenging to fabricate large and complex functional tissues due mainly to the limited diffusion capability of hydrogels. The integration of microfluidic networks and hydrogels can greatly enhance mass transport in hydrogels and spatiotemporally control the chemical microenvironment of cells, mimicking the function of native microvessels. In this review, we present and discuss recent advances in the fabrication of microfluidic hydrogels from the viewpoint of tissue engineering. Further development of new hydrogels and microengineering technologies will have a great impact on tissue engineering.

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#3 Good Health and Well-Being

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Collaboration types
Domestic collaboration
International collaboration
Web of Science research areas
Engineering, Biomedical
Materials Science, Biomaterials
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