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Journal article
Microtubules in neurons as information carriers
Journal of neurochemistry, v 129(2), pp 235-239
01 Apr 2014
PMID: 24266899
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Microtubules in neurons consist of highly dynamic regions as well as stable regions, some of which persist after bouts of severing as short mobile polymers. Concentrated at the plus ends of the highly dynamic regions are microtubule plus end tracking proteins called +TIPs that can interact with an array of other proteins and structures relevant to the plasticity of the neuron. It is also provocative to ponder that short mobile microtubules might similarly convey information with them as they transit within the neuron. Thus, beyond their known conventional functions in supporting neuronal architecture and organelle transport, microtubules may act as information carriers' in the neuron.
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Details
- Title
- Microtubules in neurons as information carriers
- Creators
- Erik W. Dent - University of Wisconsin–MadisonPeter W. Baas - Drexel University
- Publication Details
- Journal of neurochemistry, v 129(2), pp 235-239
- Publisher
- Wiley
- Number of pages
- 5
- Grant note
- R01NS080928 / NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Neurological Disorders & Stroke (NINDS) National Institutes of Health; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA P30HD003352 / EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Neurobiology and Anatomy
- Web of Science ID
- WOS:000333716700022
- Scopus ID
- 2-s2.0-84897993752
- Other Identifier
- 991019167783904721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Biochemistry & Molecular Biology
- Neurosciences