Journal article
Migrational Behavior of Human Melanoma towards Polymeric Chemoattractants
TISSUE ENGINEERING AND REGENERATIVE MEDICINE, Vol.5(4-6), pp.927-931
01 Dec 2008
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
In order to understand the molecular mechanisms of chemotaxes through reactive oxygen species(ROS), the polymeric chemoattractants with free radical generating compounds were prepared, and the migrational behavior of melanoma cells towards the samples was investigated using a Boyden chamber assay. The samples with quinoid compounds had an enhanced melanoma cells migration than control. The migrational abilities of cells were further increased when the free radicals on the surface of samples were activated with blood plasma.
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Details
- Title
- Migrational Behavior of Human Melanoma towards Polymeric Chemoattractants
- Creators
- Kyu Nam Park - College Station Medical CenterHan Joon Kim - College Station Medical CenterJung Hee Wee - College Station Medical CenterWho Kyong Lee - Dept Obstet & Gynecol, Seoul 121040, South KoreaHeung Jae Chun - Inst Cell & Tissue Eng, Seoul 121040, South KoreaJu Woong Jang - Korea Bone Bank Co Ltd, Res Inst Biomed Eng, Seoul 153782, South KoreaRichard B. Beard - Drexel University
- Publication Details
- TISSUE ENGINEERING AND REGENERATIVE MEDICINE, Vol.5(4-6), pp.927-931
- Publisher
- Korean Tissue Engineering Regenerative Medicine Soc
- Number of pages
- 5
- Grant note
- 10030022 / Ministry of Knowledge Economy, Republic of Korea
- Resource Type
- Journal article
- Language
- English
- Identifiers
- 991019318935704721
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- Collaboration types
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Cell & Tissue Engineering
- Engineering, Biomedical