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Journal article
Mini-review: Microtubule sliding in neurons
Neuroscience letters, v 753, pp 135867-135867
14 May 2021
PMID: 33812935
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Microtubule sliding is an underappreciated mechanism that contributes to the establishment, organization, preservation, and plasticity of neuronal microtubule arrays. Powered by molecular motor proteins and regulated in part by static crosslinker proteins, microtubule sliding is the movement of microtubules relative to other microtubules or to non-microtubule structures such as the actin cytoskeleton. In addition to other important functions, microtubule sliding significantly contributes to the establishment and maintenance of microtubule polarity patterns in different regions of the neuron. The purpose of this article is to review the state of knowledge on microtubule sliding in the neuron, with emphasis on its mechanistic underpinnings as well as its functional significance.
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Details
- Title
- Mini-review: Microtubule sliding in neurons
- Creators
- Shrobona Guha - Drexel UniversityAnkita Patil - Drexel UniversityHemalatha Muralidharan - Drexel UniversityPeter W Baas - Drexel University
- Publication Details
- Neuroscience letters, v 753, pp 135867-135867
- Publisher
- Elsevier
- Grant note
- R21 AG068597 / NIA NIH HHS R01 NS028785 / NINDS NIH HHS K99 NS118117 / NINDS NIH HHS R01 NS118177 / NINDS NIH HHS
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Neurobiology and Anatomy
- Web of Science ID
- WOS:000642160100001
- Scopus ID
- 2-s2.0-85104374565
- Other Identifier
- 991019168629004721
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- Web of Science research areas
- Neurosciences