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Accepted (AM)Open Access (License Unspecified), Open
Journal article
Minimal Change Patients Versus Obvious Chronic Pancreatitis A Comparison of Classical Secretin Stimulation Testing Results
PANCREAS, v 51(1), p75
Jan 2022
PMID: 35195598
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Objectives: The objective was to assess if the peak bicarbonate level during secretin stimulation testing (SST) differs between patients with minimal change (or small duct) chronic pancreatitis (CP) versus those with obvious CP (or large duct) versus those without CP. Methods: Two hundred nineteen patient records at the University of Florida who had been referred for SST were analyzed for peak bicarbonate, total volume of juice collected, age, sex, and clinical presentation. Results: Fifty-one patients with minimal change CP were identified. Thirty-three patients were felt to have advanced CP, and 135 patients did not have CP by clinical criteria. The peak bicarbonate and total volume of pancreatic juice collected was significantly different (P < 0.001) between all 3 groups by multiple comparison testing. The peak bicarbonate of advanced CP and minimal change groups was less than controls (P < 0.001). There was a significant difference (P < 0.05) on direct testing between peak bicarbonate in advanced CP and minimal change CP. Conclusions: The peak bicarbonate and volume measured during SST differs among patients with minimal change CP, advanced CP and in disease controls. These results could be useful in diagnosing minimal change/early CP.
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Details
- Title
- Minimal Change Patients Versus Obvious Chronic Pancreatitis A Comparison of Classical Secretin Stimulation Testing Results
- Publication Details
- PANCREAS, v 51(1), p75
- Publisher
- LIPPINCOTT WILLIAMS & WILKINS; PHILADELPHIA
- Grant note
- S.N. was funded by the National Institutes of Health grant TL1TR001431.
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Drexel University
- Web of Science ID
- WOS:000759723600018
- Scopus ID
- 2-s2.0-85125156419
- Other Identifier
- 991021861207304721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Gastroenterology & Hepatology