Journal article
Minimal Clinically Important Improvement of Routine Assessment of Patient Index Data 3 in Rheumatoid Arthritis
Journal of rheumatology, v 46(1), pp 27-30
Jan 2019
PMID: 30323010
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
To estimate minimal clinically important improvement (MCII) of RAPID-3 (Routine Assessment of Patient Index Data 3) in rheumatoid arthritis (RA).
RAPID-3 was computed before and after treatment escalation in a prospective study of adults with active RA. Patient judgment of improvement was used as the standard for a receiver-operating characteristic curve, from which MCII was estimated.
Mean RAPID-3 improved from 16.3 to 11.1 between visits. MCII was -3.8 based on simultaneously optimized sensitivity and specificity, -3.5 using the 0.80 specificity criterion, and -4.1 using the Youden index.
RAPID-3 improvement of 3.8/30 units appears clinically meaningful.
Metrics
Details
- Title
- Minimal Clinically Important Improvement of Routine Assessment of Patient Index Data 3 in Rheumatoid Arthritis
- Creators
- Michael M Ward - National Institute of Arthritis and Musculoskeletal and Skin DiseasesIsabel Castrejon - Rush University Medical CenterMartin J BergmanMaria I Alba - National Institutes of HealthLori C Guthrie - National Institute of Arthritis and Musculoskeletal and Skin DiseasesTheodore Pincus - National Institute of Arthritis and Musculoskeletal and Skin Diseases
- Publication Details
- Journal of rheumatology, v 46(1), pp 27-30
- Grant note
- ZIA AR041153-12 / Intramural NIH HHS
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Medicine (Graduate)
- Web of Science ID
- WOS:000454612100006
- Scopus ID
- 2-s2.0-85059403681
- Other Identifier
- 991021916796404721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Rheumatology