Mitral Interventions in Heart Failure

Matthew M Lander; Michael I Brener; Kashish Goel; Paul C Tang; Nathan J Verlinden; Sandip Zalawadiya; JoAnn Lindenfeld; Manreet K Kanwar

doi:10.1016/j.jchf.2023.07.016

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Journal article

Open access

Peer reviewed

Mitral Interventions in Heart Failure

Matthew M Lander, Michael I Brener, Kashish Goel, Paul C Tang, Nathan J Verlinden, Sandip Zalawadiya, JoAnn Lindenfeld and Manreet K Kanwar

JACC. Heart failure, v 11(8 Pt 2), pp 1055-1069

Aug 2023

DOI: https://doi.org/10.1016/j.jchf.2023.07.016

PMID: 37611988

Featured in Collection : UN Sustainable Development Goals @ Drexel

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Abstract

Heart Failure - therapy

Humans

Mitral Valve Insufficiency - complications

Mitral Valve Insufficiency - surgery

Shock, Cardiogenic

Quality of Life

Patients with heart failure with reduced ejection fraction who have secondary mitral regurgitation (SMR) have poorer outcomes and quality of life than those without SMR. Guideline-directed medical therapy is the cornerstone of SMR treatment. Careful evaluation of landmark trials using mitral transcatheter edge-to-edge repair in SMR has led to an improved understanding of who will benefit from percutaneous interventions with emphasis on a multidisciplinary approach. The success with mitral transcatheter edge-to-edge repair in SMR has also spurred the evaluation of its role in populations that were not initially studied, such as end-stage heart failure and cardiogenic shock. A spectrum of transcatheter devices in development and clinical trials promise to further provide a growing array of management options for heart failure with reduced ejection fraction patients with symptomatic SMR.

Metrics

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10 citations in Web of Science

10 citations in Scopus

Details

Title: Mitral Interventions in Heart Failure
Creators: Matthew M Lander - Allegheny Health Network
Michael I Brener - Columbia University Irving Medical Center
Kashish Goel - Vanderbilt University
Paul C Tang - University of Michigan
Nathan J Verlinden - Allegheny Health Network
Sandip Zalawadiya - Vanderbilt University
JoAnn Lindenfeld - Vanderbilt University
Manreet K Kanwar - Allegheny Health Network
Publication Details: JACC. Heart failure, v 11(8 Pt 2), pp 1055-1069
Publisher: Elsevier
Grant note: R01 HL166140 / NHLBI NIH HHS R01 HL164416 / NHLBI NIH HHS
Resource Type: Journal article
Language: English
Academic Unit: Medicine (Graduate); Cardiology
Web of Science ID: WOS:001069411400001
Scopus ID: 2-s2.0-85168606618
Other Identifier: 991021932193504721

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Collaboration types: Domestic collaboration
Web of Science research areas: Cardiac & Cardiovascular Systems