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Modeling energy expenditure in children and adolescents using quantile regression
Journal article   Open access   Peer reviewed

Modeling energy expenditure in children and adolescents using quantile regression

Yunwen Yang, Anne L Adolph, Maurice R Puyau, Firoz A Vohra, Nancy F Butte and Issa F Zakeri
Journal of applied physiology (1985), v 115(2)
15 Jul 2013
PMID: 23640591
url
https://doi.org/10.1152/japplphysiol.00295.2013View
Published, Version of Record (VoR) Open

Abstract

accelerometry heart rate childhood quantile regression energy expenditure obesity physical activity
Advanced mathematical models have the potential to capture the complex metabolic and physiological processes that result in energy expenditure (EE). Study objective is to apply quantile regression (QR) to predict EE and determine quantile-dependent variation in covariate effects in nonobese and obese children. First, QR models will be developed to predict minute-by-minute awake EE at different quantile levels based on heart rate (HR) and physical activity (PA) accelerometry counts, and child characteristics of age, sex, weight, and height. Second, the QR models will be used to evaluate the covariate effects of weight, PA, and HR across the conditional EE distribution. QR and ordinary least squares (OLS) regressions are estimated in 109 children, aged 5–18 yr. QR modeling of EE outperformed OLS regression for both nonobese and obese populations. Average prediction errors for QR compared with OLS were not only smaller at the median τ = 0.5 (18.6 vs. 21.4%), but also substantially smaller at the tails of the distribution (10.2 vs. 39.2% at τ = 0.1 and 8.7 vs. 19.8% at τ = 0.9). Covariate effects of weight, PA, and HR on EE for the nonobese and obese children differed across quantiles ( P < 0.05). The associations (linear and quadratic) between PA and HR with EE were stronger for the obese than nonobese population ( P < 0.05). In conclusion, QR provided more accurate predictions of EE compared with conventional OLS regression, especially at the tails of the distribution, and revealed substantially different covariate effects of weight, PA, and HR on EE in nonobese and obese children.

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Collaboration types
Domestic collaboration
Web of Science research areas
Physiology
Sport Sciences
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