Journal article
Models of Spinal Cord Injury: Part 2
Neurosurgery, v 19(5), pp 763-766
01 Nov 1986
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Abstract
A mathematical model was constructed to predict motor performance in rats for 8 weeks after spinal cord injury. The model is based on experimental data generated from an investigation of the static-load technique of inducing cord injury and was derived using multiple linear regression. The regression coefficients for weight of the injury-producing load were statistically significant (P < 0.001), and it was found that the weight of the load contributes over 95% of the posttrauma motor deficit, whereas the time duration of the load resting on the cord contributes less than 5% to the deficit. Sex, pretrauma motor performance, and pretrauma body weight are insignificant covariates. The model may be used to establish expected motor deficits and to derive dose-response curves.
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Details
- Title
- Models of Spinal Cord Injury: Part 2
- Creators
- Kushner Harvey - Department of Physiology and Biophysics, Hahnemann University School of Medicine, Philadelphia, PennsylvaniaS. Markowitz Ronald - Department of Neurosurgery, Hahnemann University School of Medicine, Philadelphia, PennsylvaniaMechanic Alan - Department of Neurosurgery, Hahnemann University School of Medicine, Philadelphia, PennsylvaniaBlack Perry - Department of Neurosurgery, Hahnemann University School of Medicine, Philadelphia, Pennsylvania
- Publication Details
- Neurosurgery, v 19(5), pp 763-766
- Publisher
- LWW
- Resource Type
- Journal article
- Language
- English
- Web of Science ID
- WOS:A1986E747500007
- Scopus ID
- 2-s2.0-0022998203
- Other Identifier
- 991019319087704721
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InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Clinical Neurology
- Surgery