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Models of highly pathogenic avian influenza epidemics in commercial poultry flocks in Nigeria and Ghana
Journal article   Open access   Peer reviewed

Models of highly pathogenic avian influenza epidemics in commercial poultry flocks in Nigeria and Ghana

Sky T. K. Pelletier, Chris Rorres, Peter C. Macko, Sarah Peters and Gary Smith
Tropical animal health and production, v 44(7), pp 1681-1687
01 Oct 2012
PMID: 22476732
url
https://europepmc.org/articles/pmc3627490View
Accepted (AM)Open Access (License Unspecified) Open

Abstract

Agriculture Agriculture, Dairy & Animal Science Life Sciences & Biomedicine Science & Technology Veterinary Sciences
State-scale and premises-scale gravity models for the spread of highly pathogenic avian influenza (H5N1) in Nigeria and Ghana were used to provide a basis for risk maps for future epidemics and to compare and rank plausible culling and vaccination strategies for control. Maximum likelihood methods were used to fit the models to the 2006-2007 outbreaks. The sensitivity and specificity of the state-scale model-generated probabilities that any given state would be involved in an epidemic were each 57 %. The premises-based model indicated that reactive, countrywide vaccination strategies, in which the order in which flocks are vaccinated was strictly determined by known risk factors for infection, were more effective in reducing the final size of the epidemic and the epidemic impact than vaccinating flocks at random or ring vaccination. The model suggests that an introduction of highly pathogenic avian influenza (H5N1) into Ghana had a high chance (84 %) of causing a major outbreak. That this did not happen was most probably a result of the very swift Ghanaian response to news of the first introductions.

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Web of Science research areas
Agriculture, Dairy & Animal Science
Veterinary Sciences
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