Journal article
Molecular epidemiology and cancer prevention
Cancer detection and prevention, v 14(6), pp 639-645
01 Jan 1990
PMID: 2257562
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
A review of recent studies of biologic markers in populations with model exposures to carcinogens (cigarette smoke and polycyclic aromatic hydrocarbons) illustrates their potential role in cancer prevention. Data on macromolecular adducts and oncogene activation from cross-sectional, serial sampling and case-control studies demonstrate the usefulness of biologic markers in signalling a potential carcinogenic risk and in estimating the magnitude of interindividual variation within exposed groups. Recommendations for future research include nested case-control studies to establish the relationship between markers of biologic dose and effect (e.g., adducts, gene mutation, oncogene activation) and cancer risk.
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Details
- Title
- Molecular epidemiology and cancer prevention
- Creators
- F P PereraA M JeffreyP W Brandt-RaufD BrennerJ L MayerS J SmithL LatrianoK HemminkiR M Santella
- Publication Details
- Cancer detection and prevention, v 14(6), pp 639-645
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- School of Biomedical Engineering, Science, and Health Systems; Drexel University
- Web of Science ID
- WOS:A1990EF30800008
- Scopus ID
- 2-s2.0-0025684686
- Other Identifier
- 991019342444204721
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- Web of Science research areas
- Oncology