Journal article
Monitoring Cerebral Oxygenation During Neonatal Cardiac Surgery: Limitations of Conventional NIRS
Pediatric anesthesia
10 Apr 2026
PMID: 41960715
Featured in Collection : Drexel's Newest Publications
Abstract
Congenital heart disease (CHD) is the most commonly diagnosed congenital disorder, and approximately one-third of affected children have critical CHD requiring surgical intervention in the neonatal period [1]. Improved survival of children born with critical CHD over the last few decades has highlighted the increased risk for neurodevelopmental disability in these patients. Although this risk is multifactorial, intraoperative risk factors such as use and duration of deep hypothermic circulatory arrest (DHCA), cooling duration and target temperature, and use and flow rate of regional cerebral perfusion have been linked to neurologic injury and poor outcomes [2-4]. Anesthesiologists rely on real-time monitoring of cerebral oxygen saturation with near-infrared spectroscopy (NIRS) to assess whether the brain is receiving adequate oxygen delivery during surgery. Failure to detect insufficient oxygen delivery impairs the ability to develop clinical protocols to mitigate this intraoperative risk.
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Details
- Title
- Monitoring Cerebral Oxygenation During Neonatal Cardiac Surgery: Limitations of Conventional NIRS
- Creators
- Nicolina R. Ranieri - Drexel University, School of Biomedical Engineering, Science, and Health SystemsRodrigo M. Forti - Children's Hospital of PhiladelphiaWesley B. Baker - Children's Hospital of PhiladelphiaSusan C. Nicolson - Children's Hospital of PhiladelphiaJennifer M. Lynch - Children's Hospital of Philadelphia
- Publication Details
- Pediatric anesthesia
- Publisher
- Wiley
- Number of pages
- 3
- Grant note
- CHD Coalition
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- School of Biomedical Engineering, Science, and Health Systems
- Web of Science ID
- WOS:001737326800001
- Scopus ID
- 2-s2.0-105035432002
- Other Identifier
- 991022180001204721