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Monitoring Cerebral Oxygenation During Neonatal Cardiac Surgery: Limitations of Conventional NIRS
Journal article   Open access

Monitoring Cerebral Oxygenation During Neonatal Cardiac Surgery: Limitations of Conventional NIRS

Nicolina R. Ranieri, Rodrigo M. Forti, Wesley B. Baker, Susan C. Nicolson and Jennifer M. Lynch
Pediatric anesthesia
10 Apr 2026
PMID: 41960715
Featured in Collection :   Drexel's Newest Publications
url
https://doi.org/10.1002/pan.70183View
Published, Version of Record (VoR) Open CC BY V4.0

Abstract

Life Sciences & Biomedicine Science & Technology Anesthesiology Pediatrics
Congenital heart disease (CHD) is the most commonly diagnosed congenital disorder, and approximately one-third of affected children have critical CHD requiring surgical intervention in the neonatal period [1]. Improved survival of children born with critical CHD over the last few decades has highlighted the increased risk for neurodevelopmental disability in these patients. Although this risk is multifactorial, intraoperative risk factors such as use and duration of deep hypothermic circulatory arrest (DHCA), cooling duration and target temperature, and use and flow rate of regional cerebral perfusion have been linked to neurologic injury and poor outcomes [2-4]. Anesthesiologists rely on real-time monitoring of cerebral oxygen saturation with near-infrared spectroscopy (NIRS) to assess whether the brain is receiving adequate oxygen delivery during surgery. Failure to detect insufficient oxygen delivery impairs the ability to develop clinical protocols to mitigate this intraoperative risk.

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