Journal article
Monitoring genotoxicity during the photocatalytic degradation of p-nitrophenol
Journal of applied toxicology, v 24(5), pp 395-400
Sep 2004
PMID: 15478172
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
p-Nitrophenol is a common structural unit of many pesticides and was chosen as a model compound to monitor genotoxicity during photocatalytic degradation. The genotoxicity of p-nitrophenol (PNP) and its breakdown products was measured using a bioluminescent bacterial bioassay, Vitotox. The genotoxic potential decreased with the concomitant photocatalytic degradation of the parent PNP concentration. The rate of genotoxicity reduction was slower than the rate of removal of the parent PNP, due to the formation of genotoxic by-products. After 6 h of photocatalytic treatment the total genotoxicity was removed. These results indicate that bioassays can be used as a simple and highly sensitive method for monitoring the general toxicity of chemical pollutants before, during and after photocatalytic treatment or other destructive processes.
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Details
- Title
- Monitoring genotoxicity during the photocatalytic degradation of p-nitrophenol
- Creators
- M Shani Sekler - Institute for Applied Biosciences, Ben-Gurion University, PO Box 653, Beer-Sheva 84105, IsraelY LeviB PolyakA NovoaP S M DunlopJ A ByrneR S Marks
- Publication Details
- Journal of applied toxicology, v 24(5), pp 395-400
- Publisher
- Wiley; England
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Surgery
- Web of Science ID
- WOS:000224592100014
- Scopus ID
- 2-s2.0-6944250150
- Other Identifier
- 991014878361504721
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- Collaboration types
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Toxicology