Journal article
Motor primitives and synergies in the spinal cord and after injury--the current state of play
Annals of the New York Academy of Sciences, v 1279(1)
Mar 2013
PMID: 23531009
Abstract
Modular pattern generator elements, also known as burst synergies or motor primitives, have become a useful and important way of describing motor behavior, albeit controversial. It is suggested that these synergy elements may constitute part of the pattern-shaping layers of a McCrea/Rybak two-layer pattern generator, as well as being used in other ways in the spinal cord. The data supporting modular synergies range across species including humans and encompass motor pattern analyses and neural recordings. Recently, synergy persistence and changes following clinical trauma have been presented. These new data underscore the importance of understanding the modular structure of motor behaviors and the underlying circuitry to best provide principled therapies and to understand phenomena reported in the clinic. We discuss the evidence and different viewpoints on modularity, the neural underpinnings identified thus far, and possible critical issues for the future of this area.
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Details
- Title
- Motor primitives and synergies in the spinal cord and after injury--the current state of play
- Creators
- Simon F Giszter - Department of Neurobiology and Anatomy, Drexel University College of Medicine, Philadelphia, PA 19129, USA. sgiszter@drexelmed.eduCorey B Hart
- Publication Details
- Annals of the New York Academy of Sciences, v 1279(1)
- Publisher
- Wiley; United States
- Grant note
- R01 NS072651 / NINDS NIH HHS R01 NS054894 / NINDS NIH HHS NS54894 / NINDS NIH HHS R01 NS040412 / NINDS NIH HHS NS40412 / NINDS NIH HHS
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Neurobiology and Anatomy
- Web of Science ID
- WOS:000325688000013
- Scopus ID
- 2-s2.0-84875607958
- Other Identifier
- 991014878121204721
InCites Highlights
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- Web of Science research areas
- Neurosciences