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Journal article
Multilevel Factors for Adiposity Change in a Population-Based Prospective Study of Black Breast Cancer Survivors
Journal of clinical oncology, v 40(20), pp 2213-2223
25 Mar 2022
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
PURPOSE
Unfavorable weight change after breast cancer diagnosis increases the risk of mortality, but individual and neighborhood risk factors affecting postdiagnosis weight and body fat changes are unclear among Black women, who have higher rates of obesity and mortality than any other racial/ethnic group.
METHODS
Adiposity changes during the period approximately 10 months-24 months after diagnosis were evaluated among 785 women diagnosed between 2012 and 2018 and enrolled in the Women's Circle of Health Follow-Up Study, a population-based prospective cohort of Black breast cancer survivors in New Jersey. Multilevel factors for weight and fat mass change (with gain or loss defined as a relative difference of 3% or more, and considering whether changes were intentional or unintentional) were estimated using multivariable polytomous logistic regressions and multilevel models.
RESULTS
Adiposity gain was prevalent: 28% and 47% gained weight and body fat, respectively, despite a high baseline prevalence of overweight or obesity (86%). Risk factors for fat mass gain included receiving chemotherapy (relative risk ratio: 1.59, 95% CI, 1.08 to 2.33) and residing in neighborhoods with a greater density of fast-food restaurants (relative risk ratio comparing highest with lowest tertile: 2.18, 95% CI, 1.38 to 3.46); findings were similar for weight gain. Only 9% of women had intentional weight loss, and multilevel risk factors differed vastly from unintentional loss.
CONCLUSION
Both individual and neighborhood factors were associated with adiposity change among Black breast cancer survivors. Residential environment characteristics may offer clinically meaningful information to identify cancer survivors at higher risk for unfavorable weight change and to address barriers to postdiagnosis weight management.
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Details
- Title
- Multilevel Factors for Adiposity Change in a Population-Based Prospective Study of Black Breast Cancer Survivors
- Creators
- Bo Qin - Cancer Epidemiology and Health Outcomes, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ.Kate Kim - Rutgers, The State University of New JerseyNoreen Goldman - Office of Population ResearchAndrew G. Rundle - Columbia UniversityDhanya Chanumolu - Cancer Epidemiology and Health Outcomes, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ.Nur Zeinomar - Cancer Epidemiology and Health Outcomes, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ.Baichen Xu - Cancer Epidemiology and Health Outcomes, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ.Karen S. Pawlish - New Jersey Department of HealthChristine B. Ambrosone - Roswell Park Cancer InstituteKitaw Demissie - SUNY Downstate Medical CenterChi-Chen Hong - Roswell Park Cancer InstituteGina S. Lovasi - Drexel UniversityElisa V. Bandera - Cancer Epidemiology and Health Outcomes, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ.
- Publication Details
- Journal of clinical oncology, v 40(20), pp 2213-2223
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Urban Health Collaborative
- Web of Science ID
- WOS:000821881700006
- Scopus ID
- 2-s2.0-85133576308
- Other Identifier
- 991019168803104721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Oncology