Journal article
Mycobacterial spindle cell pseudotumor of the spinal cord: Case report and literature review
Journal of neuroimmunology, v 390, 578329
15 May 2024
PMID: 38554665
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
We report the first description of spinal cord mycobacterial spindle cell pseudotumor. A patient with newly diagnosed advanced HIV presented with recent-onset bilateral leg weakness and was found to have a hypermetabolic spinal cord mass on structural and molecular imaging. Biopsy and cultures from blood and cerebrospinal fluid confirmed spindle cell pseudotumor due to Mycobacterium avium-intracellulare. Despite control of HIV and initial reduction in pseudotumor volume on antiretrovirals and antimycobacterials (azithromycin, ethambutol, rifampin/rifabutin), he ultimately experienced progressive leg weakness due to pseudotumor reexpansion. Here, we review literature and discuss multidisciplinary diagnosis, monitoring and management challenges, including immune reconstitution inflammatory syndrome.
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Details
- Title
- Mycobacterial spindle cell pseudotumor of the spinal cord: Case report and literature review
- Creators
- Michael Tran Duong - University of PennsylvaniaAdam Ungemach - University of PennsylvaniaFaizan Malik - University of PennsylvaniaMelissa T. Duong - University of PennsylvaniaNoah Wasserman - University of PennsylvaniaKumarasen Cooper - University of PennsylvaniaAustin R. Pantel - University of PennsylvaniaJessica C. ONeil - College Station Medical CenterZsofia Szep - University of Pennsylvania
- Publication Details
- Journal of neuroimmunology, v 390, 578329
- Publisher
- Elsevier
- Number of pages
- 6
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Infectious Diseases (and HIV Medicine)
- Web of Science ID
- WOS:001289218700001
- Scopus ID
- 2-s2.0-85189068698
- Other Identifier
- 991021962287604721
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InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Immunology
- Neurosciences