Logo image
Back
Myocardial Recovery in Cardiogenic Shock
Journal article   Open access   Peer reviewed

Myocardial Recovery in Cardiogenic Shock

Kevin John, Adnan Khalif, Masaki Tsukashita and Manreet K Kanwar
Methodist DeBakey cardiovascular journal, v 20(4), p64
2024
DOI: https://doi.org/10.14797/mdcvj.1383
PMID: 39184158
url
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11342837View
Published, Version of Record (VoR)Open Access (License Unspecified),  Open
url
https://doi.org/10.14797/mdcvj.1383View
Published, Version of Record (VoR) Open

Abstract

Animals Humans Recovery of Function Risk Factors Shock, Cardiogenic - diagnosis Shock, Cardiogenic - etiology Shock, Cardiogenic - mortality Shock, Cardiogenic - physiopathology Shock, Cardiogenic - therapy Time Factors Treatment Outcome Ventricular Function, Left
The overarching goal of cardiogenic shock (CS) therapy is ensuring long-term survival. In recent years, increasing emphasis has been placed on analyzing mechanisms to improve outcomes in CS. This includes averting in-hospital mortality, modifying the disease process by promoting heart recovery while avoiding multiorgan failure, and circumventing complications related to both CS and treatment strategies deployed to treat CS. Heart replacement therapies represent a viable strategy for long-term survival but are restricted to a small, select percentage of patients. In this review we focus on pathophysiology of the shock state, with an emphasis on addressing reversible etiologies contributing to the decompensated state, optimizing physiological factors for recovery, and identifying therapeutic targets to promote recovery. We also review the known predictors of myocardial recovery, regardless of the etiology of CS. Lastly, we highlight the current gaps in knowledge in this field and support additional high-quality studies focusing on myocardial recovery in CS.

Metrics

3 Record Views
1 citations in Scopus

Details

Logo image