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Journal article
NMES-Facilitated Mandibular Rehabilitation for Spasticity-Related Trismus in ALS
Muscle & Nerve, Forthcoming
01 Jul 2026
PMID: 42386387
Featured in Collection : Research Supported by Drexel Libraries' OA Programs
Abstract
Trismus is a debilitating manifestation of upper motor neuron predominant disease that may occur in individuals with amyotrophic lateral sclerosis (ALS) [1]. Increased tone and spasticity of the jaw-closing musculature can result in reduced oral opening, impairing oral intake, speech, oral hygiene, and overall quality of life. Treatment options for ALS-related trismus are limited and often include pharmacologic management, chemodenervation, and compensatory strategies [2, 3].
Neuromuscular electrical stimulation (NMES) has been investigated as a treatment for spasticity in other neurologic populations, including stroke and spinal cord injury [4, 5]. However, the use of NMES-facilitated mandibular rehabilitation for neurogenic trismus has not previously been reported. Given the potential adverse effects associated with interventions that weaken masticatory musculature, conservative rehabilitation approaches may represent an important treatment option before consideration of chemodenervation. We describe two patients with upper motor neuron–dominant ALS and spasticity-related trismus who underwent a combined NMES and mandibular range-of-motion rehabilitation program.
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Details
- Title
- NMES-Facilitated Mandibular Rehabilitation for Spasticity-Related Trismus in ALS
- Creators
- Kelly Salmon (Corresponding Author) - Drexel University, Speech-Language PathologyHristelina Ilieva - Thomas Jefferson UniversityDaniel Kelly - Thomas Jefferson University
- Publication Details
- Muscle & Nerve, Forthcoming
- Publisher
- Wiley
- Number of pages
- 4
- Grant note
- Salus University through an Internal Faculty Research
This work was supported by the Salus University through an Internal Faculty Research Grant. The funding source had no role in study design, data collection, analysis, interpretation, or manuscript preparation.
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Speech-Language Pathology
- Web of Science ID
- WOS:001809224900001
- Other Identifier
- 991022193393804721
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- Web of Science research areas
- Clinical Neurology
- Neurosciences