Journal article
Nanoscale Shear Deformation Mechanisms of Opposing Cartilage Aggrecan Macromolecules
Biophysical journal, v 93(5), pp L23-L25
22 Jun 2007
PMID: 17586571
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
The nanoscale shear deformation behavior of two opposing end-grafted aggrecan layers was studied in aqueous solutions using atomic force microscopy, and was observed to depend markedly on bath ionic strength, the presence of calcium ions, and the applied lateral displacement rate. These results provide molecular-level insights into the contribution of aggrecan deformation mechanisms to cartilage tissue-level material properties.
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Details
- Title
- Nanoscale Shear Deformation Mechanisms of Opposing Cartilage Aggrecan Macromolecules
- Creators
- Lin HanDelphine DeanPan MaoChristine OrtizAlan J. Grodzinsky
- Publication Details
- Biophysical journal, v 93(5), pp L23-L25
- Publisher
- The Biophysical Society
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- School of Biomedical Engineering, Science, and Health Systems
- Web of Science ID
- WOS:000248722200001
- Scopus ID
- 2-s2.0-34548648016
- Other Identifier
- 991019187077404721
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- Web of Science research areas
- Biophysics