Journal article
Nationwide Trends in Cardiovascular and Cerebrovascular Diseases and Outcomes Among Young Adults (18-39 years) Hospitalized With Comorbid Depression
Curēus (Palo Alto, CA), v 12(9), 10640
24 Sep 2020
PMID: 33133810
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Background
Modern-day studies that assess temporal trends in cardiovascular and cerebrovascular events (CCE) and outcomes among the young population in the United States (US) with depression remain limited.
Methods
We compared baseline demographics, comorbidities, all-cause mortality, acute myocardial infarction (AMI), percutaneous coronary interventions (PCI), arrhythmia, stroke, and venous thromboembolism (VTE) among hospitalized young adults (18-39 years) with vs. without depression using the National Inpatient Sample (NIS) from 2007 to 2014.
Results
A total of 3,575,275 patients out of 63,020,008 hospitalized young adults had comorbid depression (5.7%; median 31 years, 71.3% females). The depressed cohort more often comprised of older, white, male, and non-electively admitted patients. Higher rates of comorbidities, all-cause mortality, PCI, arrhythmia, VTE, and stroke were observed among the depressed cohort. The rising trend in all-cause mortality was observed among the depressed against a stable trend in the non-depressed. The prevalence of AMI remained stable among depressed with consistent upsurges in arrhythmia and stroke. Those with depression had extended hospital stay, higher hospitalization charges, and were more often transferred to other facilities or discharged against advice.
Conclusions
Rising trends of inpatient mortality, CCE, and higher resource utilization among young adults with depression are concerning and warrants a multidisciplinary approach to improve quality of life and outcomes.
Metrics
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Details
- Title
- Nationwide Trends in Cardiovascular and Cerebrovascular Diseases and Outcomes Among Young Adults (18-39 years) Hospitalized With Comorbid Depression
- Creators
- Rupak Desai - Veterans Health AdministrationVijaya Lakhsmi Valaparla - The University of Texas Health Science Center at San AntonioHee Kong Fong - University of California Davis Medical CenterZainab J Gandhi - CU Shah Medical College and HospitalYash Varma - Government Medical College BhavnagarKaksha Varma - Zucker Hillside HospitalMir Z Ali KhanBashar Dawood - St. Vincent's Medical CenterVirmitra Desai - University of North TexasSejal Savani - New York UniversityRajkumar Doshi - University of Nevada, RenoZeeshan Mansuri - Texas Tech University Health Sciences Center
- Publication Details
- Curēus (Palo Alto, CA), v 12(9), 10640
- Publisher
- Cureus
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- General Internal Medicine
- Web of Science ID
- WOS:000572824600002
- Other Identifier
- 991021966466404721
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InCites Highlights
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- Collaboration types
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Psychiatry