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Navigating the landscape of novel meshes: comprehensive review of physicomechanical categorization of mesh for hernia repair
Journal article   Peer reviewed

Navigating the landscape of novel meshes: comprehensive review of physicomechanical categorization of mesh for hernia repair

Alynah J Adams, Jade E Smith, Iulianna C Taritsa, Mike Stigliano, Kelly Li, Arya Rao, Daniela Lee, Jose A Foppiani, Samuel J Lin and Bernard T Lee
Hernia : the journal of hernias and abdominal wall surgery, v 30(1), 261
19 Jun 2026
DOI: https://doi.org/10.1007/s10029-026-03750-3
PMID: 42319532

Abstract

Biocompatible Materials Biomechanical Phenomena Herniorrhaphy - instrumentation Humans Porosity Surgical Mesh Tensile Strength Materials Testing
In the vast landscape of commercially available and newly emerging meshes for abdominal wall repair, surgeons must understand the biomechanical advantages of current synthetic and biologic mesh materials. A librarian conducted a literature search on PubMed, Web of Science, and CENTRAL, following PRISMA guidelines, to identify relevant articles published from January 2010 to January 2024. Two independent reviewers performed all screening steps. An exploratory quantitative synthesis was performed using generalized linear models with a Gamma distribution and log link. Our study identified 30 studies describing the physico-mechanical properties of 67 unique meshes. The majority of novel mesh materials were synthetic (85.07%, n = 57), compared to biologic (14.92%, n = 10). Pore sizes ranged from 0.10 mm² to 5.0 mm². They were subcategorized as small (0.01-0.28 mm ), medium (0.28-0.79 mm ), large (0.79-3.14 mm ), and very large (> 3.14 mm ), based on previous studies, which found these denominations to be more informative than the terms "microporous" and "macroporous." Suture retention strength, tensile strength, and burst strength were compared. Synthetic medium- to large-pore mesh performed sufficiently to withstand intra-abdominal pressures in terms of burst strength (>50 N/cm), tensile strength (>50 N/cm), and suture retention (>20 N) compared to small-pore synthetic mesh. Among biologic meshes, cross-linked biologic meshes demonstrated strong tensile and suture-retention strengths; however, data on other biomechanical properties were lacking. These results demonstrate the need to understand how the structural characteristics of each fully mesh design, such as fabrication technique and pore size, in conjunction with mechanical properties such as tensile strength, burst strength, and suture retention strength, influence clinical outcomes.

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