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Near infrared diffuse optical tomography: improving the quality of care in chronic wounds of patients with diabetes
Journal article   Peer reviewed

Near infrared diffuse optical tomography: improving the quality of care in chronic wounds of patients with diabetes

Elisabeth S Papazoglou, Michael S Weingarten, Leonid Zubkov, Linda Zhu, Som Tyagi and Kambiz Pourezaei
Biomedical instrumentation & technology, v 41(1), pp 83-87
Jan 2007
PMID: 17330447

Abstract

Animals Chronic Disease Diabetes Mellitus Models, Animal Monitoring, Physiologic - instrumentation Quality of Health Care Rats Spectroscopy, Near-Infrared Tomography, Optical - instrumentation Wound Healing
A frequency domain diffuse optical tomography instrument operating in the Near Infrared region (680-830nm) has been designed and used to monitor healing in diabetic wounds in a rat animal model. Instrument design and calibration are described and preliminary data of the in vivo experiment are reported. Excellent discrimination capability between the control and the diabetic population is possible, while the time course of impaired healing in diabetic animals appears to have different optical coefficients from the normal healing in the control group.

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