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Accepted (AM)Open Access (License Unspecified), Open
Journal article
Neighborhood Disadvantage and Cumulative Biological Risk Among a Socioeconomically Diverse Sample of African American Adults: An Examination in the Jackson Heart Study
Journal of racial and ethnic health disparities, v 3(3), pp 444-456
2016
PMID: 27294737
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Objectives
Neighborhoods characterized by disadvantage influence multiple risk factors for chronic disease and are considered potential drivers of racial and ethnic health inequities in the USA. The objective of the present study was to examine the relationship between neighborhood disadvantage and cumulative biological risk (CBR) and the extent to which the association differs by individual income and education among a large, socioeconomically diverse sample of African American adults.
Methods
Data from the baseline examination of the Jackson Heart Study (2000–2004) were used for the analyses. The sample consisted of African American adults ages 21–85 with complete, geocoded data on CBR biomarkers and behavioral covariates (
n
= 4410). Neighborhood disadvantage was measured using a composite score of socioeconomic indicators from the 2000 US Census. Eight biomarkers representing cardiovascular, metabolic, inflammatory, and neuroendocrine systems were used to create a CBR score. We fit two-level linear regression models with random intercepts and included cross-level interaction terms between neighborhood disadvantage and individual socioeconomic status (SES).
Results
Living in a disadvantaged neighborhood was associated with greater CBR after covariate adjustment (
B
= 0.18, standard error (SE) 0.07,
p
< 0.05). Interactions showed a weaker association for individuals with ≤high school education but were not statistically significant.
Conclusion
Disadvantaged neighborhoods contribute to poor health among African American adults via cumulative biological risk. Policies directly addressing the socioeconomic conditions of these environments should be considered as viable options to reduce disease risk in this group and mitigate racial/ethnic health inequities.
Metrics
Details
- Title
- Neighborhood Disadvantage and Cumulative Biological Risk Among a Socioeconomically Diverse Sample of African American Adults: An Examination in the Jackson Heart Study
- Creators
- Sharrelle Barber - Drexel UniversityDeMarc A. Hickson - University of Mississippi Medical CenterIchiro Kawachi - Harvard UniversityS. V. Subramanian - Harvard UniversityFelton Earls - Harvard University
- Publication Details
- Journal of racial and ethnic health disparities, v 3(3), pp 444-456
- Publisher
- Springer International Publishing
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Urban Health Collaborative
- Web of Science ID
- WOS:000388198900007
- Scopus ID
- 2-s2.0-84995629809
- Other Identifier
- 991019167839104721
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InCites Highlights
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Public, Environmental & Occupational Health