Journal article
Neighborhood disadvantage and the incidence of dementia in US Black women
Alzheimer's & dementia, v 21(4), e70125
Apr 2025
PMID: 40189829
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
We investigated the association of neighborhood disadvantage with the incidence of Alzheimer's disease and related dementias (ADRD) in the longitudinal Black Women's Health Study (BWHS).
The study included 10,915 BWHS participants enrolled in Medicare for at least 1 year from 2012 to 2020. The Area Deprivation Index (ADI) was assigned to participant residential block groups over follow-up. ADRD cases were identified from Medicare files.
Age- and education-adjusted hazard ratios (HRs) for ADRD increased as neighborhood disadvantage increased, to 1.42 (95% confidence interval [CI] 1.06-1.91) in the most disadvantaged quintile compared to the least disadvantaged quintile, with a significant linear trend (p = 0.012). Associations remained, although somewhat attenuated, when individual income was controlled.
The present study adds to the evidence showing an association between living in a disadvantaged neighborhood and poorer brain health. The area-level association of deprivation with ADRD was in part explained by individual differences in socioeconomic status (SES).
The study assessed neighborhood deprivation in the largest cohort of US Black women. Cases of dementia were ascertained from Medicare claims files over 9 years of follow-up. Higher levels of area deprivation were associated with higher dementia risk.
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Details
- Title
- Neighborhood disadvantage and the incidence of dementia in US Black women
- Creators
- Patricia F Coogan (Corresponding Author) - Boston UniversityLauren Delp - Boston UniversityJacqueline N Hicks - Boston UniversityTanisha G Hill-Jarrett - University of California, San FranciscoKasim Ortiz - Drexel UniversityBryan D James - Rush UniversityZinzi Bailey - University of MinnesotaLisa L Barnes - Rush UniversityLynn Rosenberg - Boston University
- Publication Details
- Alzheimer's & dementia, v 21(4), e70125
- Publisher
- Wiley
- Number of pages
- 8
- Grant note
- R01AG077948 / NIH HHS U01CA164974 / NCI NIH HHS R01AG072559 / NIH HHS
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Health Management and Policy
- Web of Science ID
- WOS:001460030600001
- Scopus ID
- 2-s2.0-105002113527
- Other Identifier
- 991022047282404721
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- Collaboration types
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Clinical Neurology