Journal article
Neighborhood environment and risk of ischemic stroke : The brain attack surveillance in corpus christi (BASIC) project
American journal of epidemiology, v 165(3), pp 279-287
01 Feb 2007
PMID: 17077168
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
The authors explored whether neighborhood-level characteristics are associated with ischemic stroke and whether the association differs by ethnicity, age, and gender. Using data from the Brain Attack Surveillance in Corpus Christi Project (January 2000–June 2003), they identified cases of ischemic stroke (n = 1,247) from both hospital and out-of-hospital sources. Census tracts served as proxies for neighborhoods, and neighborhood socioeconomic status scores were constructed from census variables (higher scores represented less disadvantage). In Poisson regression analyses comparing the 90th percentile of neighborhood score with the 10th, the relative risk of stroke was 0.49 (95% confidence interval (CI): 0.41, 0.58). After adjustment for age, gender, and ethnicity, this association was attenuated (relative risk (RR) = 0.79, 95% CI: 0.63, 1.00). There was no ethnic difference in the association of score with stroke (p for interaction = 0.79). Significant effect modification was found for age (p for interaction < 0.001) and gender (p for interaction = 0.04), with increasing scores being protective against stroke in men and younger persons. Associations were attenuated after adjustment for education (men: RR = 0.77, 95% CI: 0.55, 1.07; persons aged <65 years: RR = 0.65, 95% CI: 0.41, 1.02). Neighborhood characteristics may influence stroke risk in certain gender and age groups. Mechanisms for these associations should be examined.
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Details
- Title
- Neighborhood environment and risk of ischemic stroke : The brain attack surveillance in corpus christi (BASIC) project
- Creators
- L. D Lisabeth - University of MichiganA. V DIEZ ROUX - University of MichiganJ. D Escobar - University of MichiganM. A Smith - University of MichiganL. B Morgenstern - University of Michigan
- Publication Details
- American journal of epidemiology, v 165(3), pp 279-287
- Publisher
- Oxford University Press
- Number of pages
- 9
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Urban Health Collaborative; Epidemiology and Biostatistics
- Web of Science ID
- WOS:000243811300006
- Scopus ID
- 2-s2.0-33846628998
- Other Identifier
- 991020112125204721
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- Web of Science research areas
- Public, Environmental & Occupational Health