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Neurogenesis: is the adult stem cell young or old?
Journal article   Open access   Peer reviewed

Neurogenesis: is the adult stem cell young or old?

Jerome Ricard and Daniel J Liebl
IUBMB life, v 56(1), pp 1-6
Jan 2004
PMID: 14992373
url
https://doi.org/10.1080/15216540310001659452View
Published, Version of Record (VoR) Open

Abstract

Adult Animals Cell Differentiation Cell Division Cell Movement Cellular Senescence Central Nervous System - injuries Humans Neurons - cytology Stem Cell Transplantation Stem Cells - cytology
Stem cell biology is one of the most exciting, controversial, and debated fields in science today. It has been suggested that neuronal replacement therapy using stem cell transplants may be one possible answer to a host of neuropathological disorders including spinal cord injury, stroke, and neurodegenerative diseases. Important sources for stem cells include the developing embryo and adult central nervous system, but will these populations of cells exhibit similar behavior and responses to stimuli? This review will discuss some important similarities and differences between the embryonic and adult stem cell, as well as the basis for developing therapeutic approaches for stem cell replacement.

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Web of Science research areas
Biochemistry & Molecular Biology
Cell Biology
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