Journal article
Neuroimaging Correlates of Dementia Rating Scale Performance at Baseline and 12-Month Follow-up among Patients with Vascular Dementia
Journal of geriatric psychiatry and neurology, v 16(4), pp 240-244
Dec 2003
PMID: 14653434
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
The authors previously reported that subcortical hyperintensity (SH) and whole-brain volume (WBV) each covary with different subscale scores of the Mattis Dementia Rating Scale (MDRS) among vascular dementia (VaD) patients. The present longitudinal analysis examined these relationships for change. The authors found that SH volume increased and WBV decreased significantly over 12 months. At baseline, SH volume accounted for significant variance in MDRS total score and every subscale score, except Memory. WBV was unrelated to any MDRS measure. After 12 months, SH volume was related only to the Construction subscale score, whereas WBV accounted for the majority of variance in Attention and Memory subscale performance. These findings indicate that although SH volume increases with disease progression, the relative impact of SH volume on cognitive status decreases among patients with advanced VaD.
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Details
- Title
- Neuroimaging Correlates of Dementia Rating Scale Performance at Baseline and 12-Month Follow-up among Patients with Vascular Dementia
- Creators
- Lawrence H. Sweet - Brown UniversityRobert H. Paul - Brown University Medical School.Ronald A. Cohen - Brown University Medical SchoolDavid Moser - University of IowaBrian R. Ott - Brown University Medical School.Norman Gordon - Brown University Medical School.Jeff N. Browndyke - Brown University Medical SchoolPari Shah - Brown University Medical School.Kelly D. Garrett - Drexel UniversityNancy C Gordon - Medicine (Graduate)
- Publication Details
- Journal of geriatric psychiatry and neurology, v 16(4), pp 240-244
- Publisher
- Sage
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Medicine (Graduate)
- Web of Science ID
- WOS:000223380500009
- Scopus ID
- 2-s2.0-0344872704
- Other Identifier
- 991019167894104721
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InCites Highlights
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Clinical Neurology
- Geriatrics & Gerontology
- Psychiatry