Journal article
Newborn Infant With Mothball Toxicity Due to Maternal Ingestion
Pediatrics (Evanston), v 143(6)
01 Jun 2019
PMID: 31064798
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Chronic maternal ingestion of mothballs during the third trimester of pregnancy causes severe hemolytic anemia and pulmonary hypertension in the mother's newborn. Naphthalene poisoning due to exposure to mothballs is a common cause of toxicity in children worldwide. Naphthalene toxicity is known to cause hemolytic anemia, methemoglobinemia, and hepatic and renal injury. Neonates are more susceptible to the effects of oxidative stress from naphthalene because of their low glutathione stores and immaturity of hepatic enzymes. However, there are no reported cases of chronic fetal exposure to naphthalene during pregnancy. We report a novel case of chronic fetal exposure to naphthalene-containing mothballs that occurred from the second trimester through the third trimester of pregnancy. Our patient presented with hyperbilirubinemia, requiring exchange transfusion, severe hemolytic anemia, pulmonary hypertension, respiratory failure, and renal failure and progressed to develop bronze baby syndrome. Pregnant mothers should be diligently screened for such exposures and if found should receive psychiatric evaluation and counseling to prevent such devastating effects in neonates.
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Details
- Title
- Newborn Infant With Mothball Toxicity Due to Maternal Ingestion
- Creators
- Mitali Sahni - St. Christopher's Hospital for ChildrenYanick Vibert - St. Christopher's Hospital for ChildrenVineet Bhandari - St. Christopher's Hospital for ChildrenOgechukwu Menkiti - St. Christopher's Hospital for Children
- Publication Details
- Pediatrics (Evanston), v 143(6)
- Publisher
- Amer Acad Pediatrics
- Number of pages
- 5
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Pediatrics; Community Health and Prevention
- Web of Science ID
- WOS:000474925600030
- Scopus ID
- 2-s2.0-85067218771
- Other Identifier
- 991019167592204721
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- Web of Science research areas
- Pediatrics