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Nicotine Content from Cigarettes Submerged in Soda
Journal article   Open access   Peer reviewed

Nicotine Content from Cigarettes Submerged in Soda

Muhammed Ershad, Joris Beld, Ahmed Mostafa, Maricel Dela Cruz, David Vearrier and Michael I Greenberg
Journal of medical toxicology, v 16(4), pp 452-457
Oct 2020
DOI: https://doi.org/10.1007/s13181-020-00766-8
PMID: 32180139
Featured in Collection :   UN Sustainable Development Goals @ Drexel
url
https://doi.org/10.1007/s13181-020-00766-8View
Published, Version of Record (VoR)Open Access (License Unspecified),  Open

Abstract

Carbonated Beverages Chromatography, Liquid Nicotine - analysis Nicotinic Agonists - analysis Spectrometry, Mass, Electrospray Ionization Time Factors Tobacco Products - analysis
Cigarettes and other tobacco products may be extinguished by submersion in liquids in beverage cans or bottles. Cases of nicotine poisoning in children have been reported following ingestion of such liquids. The aim of this study is to analyze the variability of nicotine concentrations with respect to number of cigarettes immersed and the duration of immersion in a soda can METHODS: One unsmoked cigarette was immersed in a cola containing soda can. Three separate samples of the mixture were obtained at different intervals of time post immersion up to 1 week. At the same time, a set of four cola cans were immersed with an increasing number of unsmoked cigarettes and samples obtained. All the samples were then analyzed for nicotine concentrations using liquid chromatography-mass spectrometry. The mean concentration of nicotine measured over the course of 6 hours from one full cigarette in 55 ml of a cola beverage was 0.48 mg/ml. Nicotine concentrations steadily increased in the first 6 hours following submersion, after which, the levels plateaued (r = 0.530, n = 18, p = 0.024). There was a strong positive correlation between nicotine concentrations and the number of cigarettes (r = 0.967, n = 12, p = 3e-7). The mean concentration of nicotine measured over the course of 6 hours from one immersed cigarette can be potentially toxic especially to children. Nicotine concentrations are positively correlated with the number of cigarettes and time of immersion.

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Collaboration types
Domestic collaboration
Web of Science research areas
Toxicology
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