Journal article
Nitric oxide regulation of microvascular oxygen
Antioxidants & redox signaling, v 9(7), pp 829-843
Jul 2007
PMID: 17508909
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
The role of nitric oxide (NO) as a highly diffusible free radical gaseous vasodilator is intrinsically linked to the control of blood flow and oxygen (O(2)) delivery to tissue. NO also is involved in regulating mitochondrial O(2) metabolism, growth of new blood vessels, and blood oxygenation through control of respiratory ventilation. Hemoglobin and myoglobin may help to conserve NO for subsequent release of a NO-related vasoactive species under hypoxic conditions. NO has a major role in regulating microvascular O(2), and dysfunctional NO signaling is associated with the pathogenesis of metabolic and cardiovascular diseases.
Metrics
Details
- Title
- Nitric oxide regulation of microvascular oxygen
- Creators
- Donald G Buerk - University of Pennsylvania
- Publication Details
- Antioxidants & redox signaling, v 9(7), pp 829-843
- Publisher
- Mary Ann Liebert
- Grant note
- EY09269 / NEI NIH HHS HL068164 / NHLBI NIH HHS AT00428 / NCCIH NIH HHS
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- School of Biomedical Engineering, Science, and Health Systems
- Web of Science ID
- WOS:000246646200004
- Scopus ID
- 2-s2.0-34250339307
- Other Identifier
- 991019231645104721
UN Sustainable Development Goals (SDGs)
This publication has contributed to the advancement of the following goals:
InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Biochemistry & Molecular Biology
- Endocrinology & Metabolism