Journal article
Nonequilibrium Plasma-Activated Antimicrobial Solutions are Broad-Spectrum and Retain their Efficacies for Extended Period of Time
Plasma processes and polymers, v 10(6), pp 544-555
01 Jun 2013
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
By applying dielectric-barrier discharge nonthermal plasma technique, we have treated fluids and generated antimicrobial solutions, tested for properties such as changes in pH, temperature, delay time, holding time, fluid-aging, and detection and comparison of acid and hydrogen peroxide. All plasma-treated solutions showed strong biocidal activity, and among them, NAC solution was the most powerful, inactivated biofilms of tested microorganisms in 15 min of holding time. During accelerated aging experiments, plasma-treated NAC solution exhibited the equivalent of two years of shelf. These results indicate that it retained its antimicrobial properties for an extended period against a wide range of multidrug-resistant pathogens, making it an excellent candidate for further testing in vivo.
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Details
- Title
- Nonequilibrium Plasma-Activated Antimicrobial Solutions are Broad-Spectrum and Retain their Efficacies for Extended Period of Time
- Creators
- Utku K. Ercan - Drexel UniversityHong Wang - Drexel UniversityHaifeng Ji - Drexel UniversityGregory Fridman - Drexel UniversityAri D. Brooks - Drexel UniversitySuresh G. Joshi - Drexel University
- Publication Details
- Plasma processes and polymers, v 10(6), pp 544-555
- Publisher
- Wiley
- Number of pages
- 12
- Grant note
- Ministry of National Education, Government of Turkey; Ministry of National Education - Turkey Department of Surgery, Drexel University College of Medicine
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- School of Biomedical Engineering, Science, and Health Systems; Surgery; Chemistry
- Web of Science ID
- WOS:000320104600006
- Scopus ID
- 2-s2.0-84878734051
- Other Identifier
- 991019168383204721
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InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Physics, Applied
- Physics, Condensed Matter
- Physics, Fluids & Plasmas
- Polymer Science