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Nonequilibrium Plasma-Activated Antimicrobial Solutions are Broad-Spectrum and Retain their Efficacies for Extended Period of Time
Journal article   Peer reviewed

Nonequilibrium Plasma-Activated Antimicrobial Solutions are Broad-Spectrum and Retain their Efficacies for Extended Period of Time

Utku K. Ercan, Hong Wang, Haifeng Ji, Gregory Fridman, Ari D. Brooks and Suresh G. Joshi
Plasma processes and polymers, v 10(6), pp 544-555
01 Jun 2013

Abstract

Physical Sciences Physics Physics, Applied Physics, Condensed Matter Physics, Fluids & Plasmas Polymer Science Science & Technology
By applying dielectric-barrier discharge nonthermal plasma technique, we have treated fluids and generated antimicrobial solutions, tested for properties such as changes in pH, temperature, delay time, holding time, fluid-aging, and detection and comparison of acid and hydrogen peroxide. All plasma-treated solutions showed strong biocidal activity, and among them, NAC solution was the most powerful, inactivated biofilms of tested microorganisms in 15 min of holding time. During accelerated aging experiments, plasma-treated NAC solution exhibited the equivalent of two years of shelf. These results indicate that it retained its antimicrobial properties for an extended period against a wide range of multidrug-resistant pathogens, making it an excellent candidate for further testing in vivo.

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Web of Science research areas
Physics, Applied
Physics, Condensed Matter
Physics, Fluids & Plasmas
Polymer Science
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